Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Metastasis
ADR ID BADD_A06072
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.22      Metastases
16.22.01      Metastases to unknown and unspecified sites
16.22.01.001      Metastasis
Description The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. [MeSH]
MedDRA Code 10062194
MeSH ID D009362
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Metastases NOS | Secondary carcinoma | Secondary carcinoma (known primary) | Secondary malignant neoplasm of other specified site | Secondary malignant neoplasm of other specified site, not elsewhere classified | Secondary malignant neoplasm of other specified sites | Secondary malignant neoplasm of respiratory and digestive systems | Metastasis | Synchronous metastases | Metachronous metastasis | Neoplasm Metastasis | Metastases, Neoplasm | Neoplasm Metastases | Metastases | Metastasis, Neoplasm
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02392Zoledronic acid--
BADD_D02412Octreotide0.001025%
BADD_D02470Nintedanib0.000112%
BADD_D02473Sodium chloride--
BADD_D02480Alectinib0.000168%
BADD_D02483Ribociclib0.000336%
BADD_D02490Apalutamide0.001401%
BADD_D02498Abemaciclib0.000302%
BADD_D02500Alpelisib0.000168%
BADD_D02503Telotristat ethyl-
BADD_D02509Brigatinib0.001511%
BADD_D02510Rucaparib0.000112%
BADD_D02524Ivosidenib0.000224%
BADD_D02548Darolutamide0.001068%
BADD_D02568Lutetium oxodotreotide lu-177-
BADD_D02586Radium ra-223 dichloride-
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