Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Ulcerative keratitis
ADR ID BADD_A06283
ADR Hierarchy
06      Eye disorders
06.04      Ocular infections, irritations and inflammations
06.04.02      Corneal infections, oedemas and inflammations
06.04.02.004      Ulcerative keratitis
10      Immune system disorders
10.02      Immune disorders NEC
10.02.01      Immune and associated conditions NEC
10.02.01.021      Ulcerative keratitis
Description Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection. [MeSH]
MedDRA Code 10064996
MeSH ID D003320
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Central corneal ulcer | Corneal ulcer marginal | Corneal ulcer NEC | Corneal ulcer, unspecified | Corneal ulceration | Mooren's ulcer | Necrosis corneal | Perforated corneal ulcer | Ring corneal ulcer | Ulcer corneal | Ulcer corneal perforated | Corneal ulcer | Corneal melt | Ulcerative keratitis | Peripheral noninfective corneal ulcer | Corneal Ulcer | Ulcer, Corneal | Keratitis, Ulcerative | Keratitides, Ulcerative | Ulcerative Keratitides | Ulcerative Keratitis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01162Insulin detemir--
BADD_D01213Isotretinoin0.001081%
BADD_D01232Ketorolac--
BADD_D01233Ketorolac tromethamine--
BADD_D01243Lamotrigine0.000110%
BADD_D01251Latanoprost0.000045%
BADD_D01275Levofloxacin0.000042%
BADD_D01290Lifitegrast0.003005%
BADD_D01308Lodoxamide tromethamine--
BADD_D01367Medrysone--
BADD_D01478Mitomycin0.000112%
BADD_D01501Moxifloxacin0.000808%
BADD_D01507Mycophenolate mofetil--
BADD_D01555Nepafenac0.003382%
BADD_D01562Nicorandil--
BADD_D01616Onabotulinumtoxina--
BADD_D01666Panitumumab--
BADD_D01668Pantoprazole0.000025%
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01799Ponatinib0.000112%
BADD_D01831Prednisolone0.000035%
BADD_D01832Prednisolone acetate0.002159%
BADD_D01834Prednisone0.000020%
BADD_D01835Pregabalin--
BADD_D01862Proparacaine0.001075%
BADD_D01933Ribavirin--
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