Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cerebral arteriosclerosis
ADR ID BADD_A06318
ADR Hierarchy
17      Nervous system disorders
17.08      Central nervous system vascular disorders
17.08.02      Central nervous system vascular disorders NEC
17.08.02.008      Cerebral arteriosclerosis
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.06      Cerebrovascular and spinal necrosis and vascular insufficiency
24.04.06.019      Cerebral arteriosclerosis
Description Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS. [MeSH]
MedDRA Code 10065559
MeSH ID D002537
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Atherosclerosis cerebral | Cerebral atherosclerosis | Cerebral arteriosclerosis | Cerebral artery atheroma | Atheroma in the circle of Willis | Basilar artery atheroma | Intracranial Arteriosclerosis | Arterioscleroses, Intracranial | Arteriosclerosis, Intracranial | Intracranial Arterioscleroses | Intracranial Atherosclerosis | Atheroscleroses, Intracranial | Atherosclerosis, Intracranial | Intracranial Atheroscleroses | Cerebral Arteriosclerosis | Arterioscleroses, Cerebral | Arteriosclerosis, Cerebral | Cerebral Arterioscleroses | Cerebral Atherosclerosis | Atheroscleroses, Cerebral | Atherosclerosis, Cerebral | Cerebral Atheroscleroses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000044%
BADD_D01133Ifosfamide--
BADD_D01521Nalidixic acid--
BADD_D01567Nilotinib0.000168%
BADD_D01954Rivaroxaban0.000063%
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