Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Acute interstitial pneumonitis
ADR ID BADD_A06391
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.01      Lower respiratory tract disorders (excl obstruction and infection)
22.01.02      Parenchymal lung disorders NEC
22.01.02.016      Acute interstitial pneumonitis
Description A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death. [MeSH]
MedDRA Code 10066728
MeSH ID D011658
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hamman-Rich syndrome | Acute interstitial pneumonitis | Pulmonary Fibrosis | Pulmonary Fibroses | Fibroses, Pulmonary | Fibrosis, Pulmonary | Alveolitis, Fibrosing | Alveolitides, Fibrosing | Fibrosing Alveolitides | Fibrosing Alveolitis | Hamman-Rich Syndrome | Hamman Rich Syndrome | Syndrome, Hamman-Rich
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00115Amiodarone0.000135%
BADD_D00129Amoxicillin0.000005%
BADD_D00280Bleomycin--
BADD_D00511Clozapine0.001223%
BADD_D00581Daptomycin0.000146%
BADD_D01397Mesalamine--
BADD_D01401Metformin0.000014%
BADD_D01653Paclitaxel0.000280%
BADD_D02093Sulfasalazine--
BADD_D02150Temozolomide0.000112%
BADD_D02331Valsartan--
BADD_D02373Warfarin0.000056%
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