Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Organising pneumonia
ADR ID BADD_A06439
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.01      Lower respiratory tract disorders (excl obstruction and infection)
22.01.02      Parenchymal lung disorders NEC
22.01.02.008      Organising pneumonia
Description An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a "pneumonia-like" illness with cough, fever, malaise, fatigue, and weight loss. Pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. There is excessive proliferation of granulation tissue within small airways and alveolar ducts. [MeSH]
MedDRA Code 10067472
MeSH ID D018549
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
BOOP | Bronchiolitis obliterans with organizing pneumonia | Cryptogenic organizing pneumonia | Cryptogenic organising pneumonia | Bronchiolitis obliterans with organising pneumonia | Organizing pneumonia | Organising pneumonia | Acute fibrinous organising pneumonia | Acute fibrinous organizing pneumonia | Cryptogenic Organizing Pneumonia | Cryptogenic Organizing Pneumonias | Organizing Pneumonia, Cryptogenic | Organizing Pneumonias, Cryptogenic | Pneumonia, Cryptogenic Organizing | Pneumonias, Cryptogenic Organizing | Bronchiolitis Obliterans Organizing Pneumonia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01397Mesalamine0.000823%
BADD_D01414Methimazole0.000202%
BADD_D01418Methotrexate--
BADD_D01445Metoprolol0.000010%
BADD_D01567Nilotinib0.000168%
BADD_D01629Osimertinib0.000168%
BADD_D01633Oxaliplatin0.000224%
BADD_D01653Paclitaxel0.000224%
BADD_D01765Phenytoin0.000956%
BADD_D01831Prednisolone0.000070%
BADD_D01834Prednisone0.000031%
BADD_D01835Pregabalin0.000156%
BADD_D01869Propylthiouracil0.014106%
BADD_D01909Ramipril0.000233%
BADD_D01933Ribavirin0.005934%
BADD_D01971Rosuvastatin0.000026%
BADD_D02010Sertraline0.000045%
BADD_D02026Simvastatin0.000015%
BADD_D02028Sirolimus--
BADD_D02060Sotalol0.000703%
BADD_D02066Spironolactone0.000110%
BADD_D02093Sulfasalazine0.000455%
BADD_D02105Tacrolimus0.002525%
BADD_D02150Temozolomide0.000839%
BADD_D02165Teriflunomide0.000362%
BADD_D02362Vinflunine--
BADD_D02369Voriconazole0.005809%
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