Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Type 1 diabetes mellitus
ADR ID BADD_A06449
ADR Hierarchy
05      Endocrine disorders
05.06      Glucose metabolism disorders (incl diabetes mellitus)
05.06.01      Diabetes mellitus (incl subtypes)
05.06.01.010      Type 1 diabetes mellitus
10      Immune system disorders
10.04      Autoimmune disorders
10.04.08      Endocrine autoimmune disorders
10.04.08.007      Type 1 diabetes mellitus
14      Metabolism and nutrition disorders
14.06      Glucose metabolism disorders (incl diabetes mellitus)
14.06.01      Diabetes mellitus (incl subtypes)
14.06.01.010      Type 1 diabetes mellitus
Description A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. [MeSH]
MedDRA Code 10067584
MeSH ID D003922
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Diabetes mellitus insulin-dependent | Diabetes mellitus juvenile onset | IDDM | Insulin dependent diabetic | Insulin-dependent diabetes mellitus | Juvenile diabetes | Type I diabetes mellitus | Type I diabetes mellitus without mention of complication | Type 1 diabetes mellitus | Immune-mediated diabetes | Diabetes Mellitus, Type 1 | Type 1 Diabetes Mellitus | Diabetes Mellitus, Type I | Type 1 Diabetes | Diabetes, Type 1 | Diabetes Mellitus, Ketosis-Prone | Diabetes Mellitus, Ketosis Prone | Ketosis-Prone Diabetes Mellitus | Diabetes, Autoimmune | Autoimmune Diabetes | Diabetes Mellitus, Juvenile-Onset | Diabetes Mellitus, Juvenile Onset | Juvenile-Onset Diabetes Mellitus | Juvenile-Onset Diabetes | Diabetes, Juvenile-Onset | Juvenile Onset Diabetes | Diabetes Mellitus, Insulin-Dependent | Diabetes Mellitus, Insulin Dependent | Insulin-Dependent Diabetes Mellitus | Diabetes Mellitus, Insulin-Dependent, 1 | Insulin-Dependent Diabetes Mellitus 1 | Insulin Dependent Diabetes Mellitus 1 | Diabetes Mellitus, Brittle | Brittle Diabetes Mellitus | Diabetes Mellitus, Sudden-Onset | Diabetes Mellitus, Sudden Onset | Sudden-Onset Diabetes Mellitus
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000066%
BADD_D00165Aripiprazole0.000555%
BADD_D00193Axitinib0.000168%
BADD_D00330Cabozantinib0.000168%
BADD_D00344Canagliflozin0.000180%
BADD_D00349Capecitabine0.000112%
BADD_D00490Clobetasol propionate0.002801%
BADD_D00511Clozapine0.004891%
BADD_D00578Dapagliflozin0.000439%
BADD_D00680Dimethyl fumarate0.001000%
BADD_D00765Empagliflozin0.000182%
BADD_D00852Etonogestrel0.000235%
BADD_D01213Isotretinoin0.001930%
BADD_D01243Lamotrigine0.000166%
BADD_D01401Metformin0.000011%
BADD_D01405Methadone0.000265%
BADD_D01414Methimazole0.000202%
BADD_D01431Methylphenidate0.000062%
BADD_D01433Methylprednisolone0.000032%
BADD_D01470Minocycline0.000944%
BADD_D01496Montelukast0.000015%
BADD_D01564Nicotine0.000940%
BADD_D01599Olanzapine0.000737%
BADD_D01645Oxycodone--
BADD_D01656Paliperidone0.001366%
BADD_D01701Pemetrexed--
BADD_D01831Prednisolone0.000105%
BADD_D01834Prednisone0.000018%
BADD_D01835Pregabalin0.000078%
BADD_D01888Quetiapine0.000082%
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