Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Acute kidney injury
ADR ID BADD_A06560
ADR Hierarchy
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.03      Renal failure and impairment
20.01.03.016      Acute kidney injury
Description A disorder characterized by the acute loss of renal function (within 2 weeks) and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction). [CTCAE] Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | Conditions in which the function of KIDNEYS deteriorates suddenly in a matter of days or even hours. It is characterized by the sudden drop in GLOMERULAR FILTRATION RATE. [MeSH]
MedDRA Code 10069339
MeSH ID D058186
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute kidney failure | Acute on chronic renal failure | Acute prerenal failure | Acute renal failure | Acute renal failure following labor and delivery | Acute renal failure following labor and delivery, postpartum condition or complication | Acute renal failure following labor and delivery, unspecified as to episode of care | Acute renal failure following labour and delivery | Acute renal failure with delivery, with mention of postpartum complication | Acute renal failure with lesion of renal cortical necrosis | Acute renal failure with lesion of renal medullary (papillary) necrosis | Acute renal failure with lesion of tubular necrosis | Acute renal failure with other specified pathological lesion in kidney | Acute renal failure, unspecified | ARF | Azotemia prerenal | Failure kidney acute | Kidney failure acute | Renal failure acute | Renal failure acute hypotensive | Renal failure acute ischaemic | Renal failure acute ischemic | Renal failure acute on chronic | Renal failure acute uratic | Renal shutdown acute | Shutdown renal | Acute renal insufficiency | Rhabdomyolysis-induced renal failure | Azotaemia prerenal | Acute oliguric renal failure | Acute kidney injury | Stage 1 acute kidney injury | Stage 2 acute kidney injury | Stage 3 acute kidney injury | Acute nonoliguric renal failure | Acute prerenal insufficiency | Acute Kidney Injury | Acute Kidney Injuries | Kidney Injuries, Acute | Kidney Injury, Acute | Acute Renal Injury | Acute Renal Injuries | Renal Injuries, Acute | Renal Injury, Acute | Renal Insufficiency, Acute | Acute Renal Insufficiencies | Renal Insufficiencies, Acute | Acute Renal Insufficiency | Kidney Insufficiency, Acute | Acute Kidney Insufficiencies | Kidney Insufficiencies, Acute | Acute Kidney Insufficiency | Kidney Failure, Acute | Acute Kidney Failures | Kidney Failures, Acute | Acute Renal Failure | Acute Renal Failures | Renal Failures, Acute | Renal Failure, Acute | Acute Kidney Failure
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00593Decitabine0.000728%
BADD_D00594Deferasirox0.027261%
BADD_D00596Deferoxamine--
BADD_D00603Delavirdine--
BADD_D00604Delavirdine mesylate--
BADD_D00605Demeclocycline--
BADD_D00606Demeclocycline hydrochloride--
BADD_D00616Desmopressin0.004277%
BADD_D00623Dexamethasone0.003051%
BADD_D00628Dexlansoprazole0.000415%
BADD_D00629Dexmedetomidine--
BADD_D00630Dexmedetomidine hydrochloride--
BADD_D00643Diamminedichloroplatinum--
BADD_D00647Diatrizoic acid--
BADD_D00648Diazepam0.001007%
BADD_D00650Dibasic potassium phosphate--
BADD_D00653Diclofenac0.001063%
BADD_D00661Didanosine--
BADD_D00668Digoxin0.005064%
BADD_D00673Dihydrogen phosphate--
BADD_D00674Diltiazem0.000438%
BADD_D00686Diphenhydramine0.001276%
BADD_D00702Dolasetron--
BADD_D00723Doxorubicin0.002295%
BADD_D00725Doxycycline0.000022%
BADD_D00730Dronedarone0.001959%
BADD_D00736Dutasteride0.000569%
BADD_D00749Efavirenz--
BADD_D00765Empagliflozin0.006507%
BADD_D00766Emtricitabine0.005599%
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