Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Transplant dysfunction
ADR ID BADD_A06765
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.02      Procedural related injuries and complications NEC
12.02.09      Transplantation complications
12.02.09.019      Transplant dysfunction
Description A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION. [MeSH]
MedDRA Code 10074860
MeSH ID D055031
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Primary graft dysfunction | Never functioning graft | Graft dysfunction | Transplant dysfunction | Primary Graft Dysfunction | Dysfunction, Primary Graft | Graft Dysfunction, Primary
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00223Belatacept--
BADD_D02105Tacrolimus--
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