Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Multiple organ dysfunction syndrome
ADR ID BADD_A06819
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.03      General signs and symptoms NEC
08.01.03.057      Multiple organ dysfunction syndrome
Description A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative. [MeSH]
MedDRA Code 10077361
MeSH ID D009102
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
MOF | Multi organ failure | Multi-organ failure | Multiorgan failure | Multiple organ failure | Multiple organ dysfunction syndrome | Multiple Organ Failure | Multiple Organ Dysfunction Syndrome | Organ Failure, Multiple | Failure, Multiple Organ | Multiple Organ Failures | MODS | Organ Dysfunction Syndrome, Multiple
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen0.000107%
BADD_D00033Acetylsalicylic acid0.000122%
BADD_D00039Acyclovir0.000107%
BADD_D00076Allopurinol--
BADD_D00103Amikacin0.000127%
BADD_D00115Amiodarone0.000808%
BADD_D00118Amitriptyline0.000048%
BADD_D00121Amlodipine0.000041%
BADD_D00129Amoxicillin0.000041%
BADD_D00130Amphetamine0.000161%
BADD_D00132Amphotericin b0.000564%
BADD_D00142Anastrozole0.000477%
BADD_D00143Anidulafungin0.000299%
BADD_D00158Aprotinin (bovine)--
BADD_D00161Argatroban0.000123%
BADD_D00169Arsenic trioxide0.000112%
BADD_D00176Atazanavir0.001203%
BADD_D00186Atovaquone0.000213%
BADD_D00194Azacitidine0.002183%
BADD_D00195Azathioprine0.003446%
BADD_D00206Aztreonam0.000049%
BADD_D00209Baclofen0.000696%
BADD_D00225Belinostat--
BADD_D00230Bendamustine0.000336%
BADD_D00271Bicalutamide0.007030%
BADD_D00277Bisoprolol0.002041%
BADD_D00284Bortezomib0.000783%
BADD_D00285Bosentan0.002407%
BADD_D00306Budesonide0.000140%
BADD_D00318Busulfan0.000504%
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