Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Multiple organ dysfunction syndrome
ADR ID BADD_A06819
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.03      General signs and symptoms NEC
08.01.03.057      Multiple organ dysfunction syndrome
Description A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative. [MeSH]
MedDRA Code 10077361
MeSH ID D009102
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
MOF | Multi organ failure | Multi-organ failure | Multiorgan failure | Multiple organ failure | Multiple organ dysfunction syndrome | Multiple Organ Failure | Multiple Organ Dysfunction Syndrome | Organ Failure, Multiple | Failure, Multiple Organ | Multiple Organ Failures | MODS | Organ Dysfunction Syndrome, Multiple
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00979Furosemide0.000153%
BADD_D00993Gadoteridol0.007113%
BADD_D01003Ganciclovir--
BADD_D01004Ganciclovir sodium--
BADD_D01008Gefitinib0.000280%
BADD_D01009Gemcitabine0.000280%
BADD_D01081Hydralazine0.000068%
BADD_D01083Hydrochlorothiazide0.000035%
BADD_D01096Hydromorphone--
BADD_D01103Hydroxychloroquine0.003719%
BADD_D01110Hydroxyurea0.000168%
BADD_D01119Ibrutinib0.001679%
BADD_D01120Ibuprofen0.000026%
BADD_D01133Ifosfamide0.000112%
BADD_D01135Iloprost0.000288%
BADD_D01136Imatinib0.001343%
BADD_D01142Imiquimod0.000439%
BADD_D01181Iopamidol0.007113%
BADD_D01182Iopromide0.039124%
BADD_D01195Irinotecan0.000392%
BADD_D01217Itraconazole0.010689%
BADD_D01230Ketoconazole0.000066%
BADD_D01231Ketoprofen0.002240%
BADD_D01242Lamivudine0.002024%
BADD_D01243Lamotrigine0.001656%
BADD_D01245Lansoprazole0.000796%
BADD_D01248Lapatinib0.000168%
BADD_D01252Leflunomide0.001500%
BADD_D01253Lenalidomide--
BADD_D01257Letrozole0.001054%
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