Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Multiple organ dysfunction syndrome
ADR ID BADD_A06819
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.03      General signs and symptoms NEC
08.01.03.057      Multiple organ dysfunction syndrome
Description A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative. [MeSH]
MedDRA Code 10077361
MeSH ID D009102
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
MOF | Multi organ failure | Multi-organ failure | Multiorgan failure | Multiple organ failure | Multiple organ dysfunction syndrome | Multiple Organ Failure | Multiple Organ Dysfunction Syndrome | Organ Failure, Multiple | Failure, Multiple Organ | Multiple Organ Failures | MODS | Organ Dysfunction Syndrome, Multiple
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01598Ofloxacin0.000083%
BADD_D01599Olanzapine0.001263%
BADD_D01633Oxaliplatin0.000839%
BADD_D01636Oxazepam0.003040%
BADD_D01637Oxcarbazepine0.000341%
BADD_D01653Paclitaxel0.000783%
BADD_D01668Pantoprazole0.000082%
BADD_D01687Pazopanib0.001343%
BADD_D01734Perflutren-
BADD_D01752Phenobarbital0.000325%
BADD_D01756Phentermine0.000164%
BADD_D01760Phenylbutyric acid0.006469%
BADD_D01765Phenytoin0.001338%
BADD_D01798Pomalidomide--
BADD_D01799Ponatinib0.000448%
BADD_D01804Posaconazole0.022223%
BADD_D01824Pravastatin0.000025%
BADD_D01831Prednisolone0.001066%
BADD_D01834Prednisone0.000282%
BADD_D01854Promethazine0.000231%
BADD_D01856Propafenone0.001463%
BADD_D01864Propofol0.002143%
BADD_D01869Propylthiouracil0.028212%
BADD_D01881Pyridostigmine0.002125%
BADD_D01888Quetiapine0.000273%
BADD_D01905Raltegravir0.002472%
BADD_D01909Ramipril0.000373%
BADD_D01920Refludan--
BADD_D01933Ribavirin0.053404%
BADD_D01938Rifaximin0.000965%
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