Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Antiphospholipid syndrome
ADR ID BADD_A06905
ADR Hierarchy
01      Blood and lymphatic system disorders
01.01      Coagulopathies and bleeding diatheses (excl thrombocytopenic)
01.01.02      Coagulopathies
01.01.02.016      Antiphospholipid syndrome
10      Immune system disorders
10.04      Autoimmune disorders
10.04.01      Blood autoimmune disorders
10.04.01.009      Antiphospholipid syndrome
18      Pregnancy, puerperium and perinatal conditions
18.02      Maternal complications of pregnancy
18.02.04      Pregnancy complicated by maternal disorders
18.02.04.002      Antiphospholipid syndrome
24      Vascular disorders
24.01      Embolism and thrombosis
24.01.01      Non-site specific embolism and thrombosis
24.01.01.029      Antiphospholipid syndrome
Description The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR). [MeSH]
MedDRA Code 10002817
MeSH ID D016736
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Antiphospholipid syndrome | Anticardiolipin antibody syndrome | Hughes syndrome | Seronegative antiphospholipid syndrome | Catastrophic antiphospholipid syndrome | Secondary antiphospholipid syndrome | Antiphospholipid Syndrome | Syndrome, Antiphospholipid | Hughes Syndrome | Syndrome, Hughes | Antiphospholipid Antibody Syndrome | Antibody Syndrome, Antiphospholipid | Antiphospholipid Antibody Syndromes | Syndrome, Antiphospholipid Antibody | Anti-Phospholipid Antibody Syndrome | Anti Phospholipid Antibody Syndrome | Antibody Syndrome, Anti-Phospholipid | Syndrome, Anti-Phospholipid Antibody | Anti-Phospholipid Syndrome | Anti Phospholipid Syndrome | Syndrome, Anti-Phospholipid
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000044%
BADD_D00129Amoxicillin0.000005%
BADD_D00142Anastrozole0.000556%
BADD_D00151Apixaban0.000716%
BADD_D00161Argatroban0.000082%
BADD_D00382Cefazolin0.000049%
BADD_D00563Dabigatran0.000979%
BADD_D00759Eltrombopag0.000343%
BADD_D01260Leuprolide acetate0.001434%
BADD_D01401Metformin0.000005%
BADD_D01470Minocycline0.000295%
BADD_D01602Olmesartan0.000210%
BADD_D01831Prednisolone0.000035%
BADD_D01954Rivaroxaban0.000982%
BADD_D02047Sodium oxybate0.000268%
BADD_D02105Tacrolimus0.000297%
BADD_D02373Warfarin0.000182%
BADD_D02383Zidovudine0.004421%
BADD_D02464Fingolimod0.000241%
The 1th Page    1    Total 1 Pages