Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Lupus nephritis
ADR ID BADD_A07374
ADR Hierarchy
10      Immune system disorders
10.04      Autoimmune disorders
10.04.03      Lupus erythematosus and associated conditions
10.04.03.011      Lupus nephritis
15      Musculoskeletal and connective tissue disorders
15.06      Connective tissue disorders (excl congenital)
15.06.02      Lupus erythematosus (incl subtypes)
15.06.02.011      Lupus nephritis
20      Renal and urinary disorders
20.05      Nephropathies
20.05.02      Nephritis NEC
20.05.02.003      Lupus nephritis
Description Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982). [MeSH]
MedDRA Code 10025140
MeSH ID D008181
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Lupus nephritis | Nephritis SLE | Nephritis systemic lupus erythematosus | SLE nephritis | Lupus-like nephritis | Lupus Nephritis | Lupus Glomerulonephritis | Nephritis, Lupus | Lupus Nephritides | Nephritides, Lupus | Glomerulonephritis, Lupus | Glomerulonephritides, Lupus | Lupus Glomerulonephritides
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00285Bosentan0.000181%
BADD_D00718Doxazosin0.000113%
BADD_D01081Hydralazine0.001057%
BADD_D01243Lamotrigine0.000221%
BADD_D01831Prednisolone0.000070%
BADD_D01834Prednisone0.000058%
BADD_D02066Spironolactone0.000055%
BADD_D02105Tacrolimus0.000297%
BADD_D02236Tofacitinib0.000241%
BADD_D02539Calcium0.000391%
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