Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Mitral valve prolapse
ADR ID BADD_A07432
ADR Hierarchy
02      Cardiac disorders
02.07      Cardiac valve disorders
02.07.01      Mitral valvular disorders
02.07.01.008      Mitral valve prolapse
Description Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA. [MeSH]
MedDRA Code 10027730
MeSH ID D008945
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Barlow's syndrome | Floppy mitral valve | Mitral leaflet prolapse | Mitral valve prolapse | Prolapsed mitral valve | Mitral Valve Prolapse | Mitral Valve Prolapses | Prolapse, Mitral Valve | Prolapses, Mitral Valve | Valve Prolapse, Mitral | Valve Prolapses, Mitral | Floppy Mitral Valve | Floppy Mitral Valves | Mitral Valve, Floppy | Mitral Valves, Floppy | Mitral Click-Murmur Syndrome | Click-Murmur Syndrome, Mitral | Mitral Click Murmur Syndrome | Syndrome, Mitral Click-Murmur | Systolic Click-Murmur Syndrome | Click-Murmur Syndrome, Systolic | Syndrome, Systolic Click-Murmur | Systolic Click Murmur Syndrome | Prolapsed Mitral Valve | Mitral Valve, Prolapsed | Mitral Valves, Prolapsed | Prolapsed Mitral Valves | Valve, Prolapsed Mitral | Valves, Prolapsed Mitral | Click-Murmur Syndrome | Click Murmur Syndrome | Click-Murmur Syndromes | Syndrome, Click-Murmur | Syndromes, Click-Murmur | Mitral Valve Prolapse Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000418%
BADD_D00156Apremilast0.000940%
BADD_D00898Finasteride0.000112%
BADD_D00932Fluoxetine0.000059%
BADD_D01213Isotretinoin0.000257%
BADD_D01285Levothyroxine0.000005%
BADD_D01567Nilotinib0.000112%
BADD_D01679Paroxetine0.000064%
BADD_D02010Sertraline0.000013%
BADD_D02029Sitagliptin0.000053%
BADD_D02047Sodium oxybate0.000402%
BADD_D02331Valsartan0.000053%
BADD_D02346Venlafaxine0.000109%
BADD_D02464Fingolimod0.000241%
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