Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Pernicious anaemia
ADR ID BADD_A07559
ADR Hierarchy
01      Blood and lymphatic system disorders
01.03      Anaemias nonhaemolytic and marrow depression
01.03.01      Anaemia deficiencies
01.03.01.003      Pernicious anaemia
07      Gastrointestinal disorders
07.17      Malabsorption conditions
07.17.01      Malabsorption syndromes
07.17.01.004      Pernicious anaemia
10      Immune system disorders
10.04      Autoimmune disorders
10.04.01      Blood autoimmune disorders
10.04.01.007      Pernicious anaemia
Description A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin B 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (Dorland, 27th ed) [MeSH]
MedDRA Code 10034695
MeSH ID D000752
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Addison's anemia | Addison-Biermer anemia | Addisonian anemia | Addisonian pernicious anaemia | Anaemia pernicious | Anemia pernicious type | Pernicious anaemia | Pernicious anaemia NOS | Pernicious anemia | Addisonian pernicious anemia | Addison-Biermer anaemia | Addisonian anaemia | Addison's anaemia | Anaemia pernicious type | Anemia, Pernicious | Pernicious Anemia | Anemia, Addison's | Anemia, Addison | Anemia, Addisons | Addison's Anemia | Addison Anemia | Addisons Anemia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone0.000334%
BADD_D00066Alendronic acid0.000176%
BADD_D00410Celecoxib0.000050%
BADD_D01285Levothyroxine0.000011%
BADD_D01401Metformin0.000030%
BADD_D01668Pantoprazole0.000033%
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