Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pickwickian syndrome
ADR ID BADD_A07565
ADR Hierarchy
01      Blood and lymphatic system disorders
01.07      Red blood cell disorders
01.07.01      Polycythaemia (excl rubra vera)
01.07.01.002      Pickwickian syndrome
17      Nervous system disorders
17.15      Sleep disturbances (incl subtypes)
17.15.04      Sleep disturbances NEC
17.15.04.007      Pickwickian syndrome
19      Psychiatric disorders
19.02      Sleep disorders and disturbances
19.02.05      Dyssomnias
19.02.05.010      Pickwickian syndrome
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.01      Breathing abnormalities
22.02.01.031      Pickwickian syndrome
Description HYPOVENTILATION syndrome in very obese persons with excessive ADIPOSE TISSUE around the ABDOMEN and DIAPHRAGM. It is characterized by diminished to absent ventilatory chemoresponsiveness; chronic HYPOXIA; HYPERCAPNIA; POLYCYTHEMIA; and long periods of sleep during day and night (HYPERSOMNOLENCE). It is a condition often related to OBSTRUCTIVE SLEEP APNEA but can occur separately. [MeSH]
MedDRA Code 10035004
MeSH ID D010845
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Pickwickian syndrome | Obesity hypoventilation syndrome | Obesity Hypoventilation Syndrome | Hypoventilation Syndrome, Obesity | Syndrome, Obesity Hypoventilation | Pickwickian Syndrome | Syndrome, Pickwickian | Obesity-Hypoventilation Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000044%
BADD_D02443Tiotropium0.000057%
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