Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Prolactin-producing pituitary tumour
ADR ID BADD_A07603
ADR Hierarchy
05      Endocrine disorders
05.03      Hypothalamus and pituitary gland disorders
05.03.05      Pituitary neoplasms
05.03.05.005      Prolactin-producing pituitary tumour
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.24      Endocrine neoplasms malignant and unspecified
16.24.07      Hormone secreting pituitary neoplasms
16.24.07.001      Prolactin-producing pituitary tumour
Description A pituitary adenoma which secretes PROLACTIN, leading to HYPERPROLACTINEMIA. Clinical manifestations include AMENORRHEA; GALACTORRHEA; IMPOTENCE; HEADACHE; visual disturbances; and CEREBROSPINAL FLUID RHINORRHEA. [MeSH]
MedDRA Code 10036831
MeSH ID D015175
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Prolactin-producing pituitary tumour | Prolactinoma | Prolactin-producing pituitary tumor | Prolactinomas | Lactotroph Adenoma | Adenoma, Lactotroph | Adenomas, Lactotroph | Lactotroph Adenomas | Prolactinoma, Familial | PRL-Secreting Pituitary Adenoma | PRL Secreting Pituitary Adenoma | PRL-Secreting Pituitary Adenomas | Pituitary Adenoma, PRL-Secreting | Pituitary Adenomas, PRL-Secreting | Prolactin-Producing Pituitary Adenoma | Pituitary Adenoma, Prolactin-Producing | Pituitary Adenomas, Prolactin-Producing | Prolactin Producing Pituitary Adenoma | Prolactin-Producing Pituitary Adenomas | Prolactin-Secreting Pituitary Adenoma | Prolactin Secreting Pituitary Adenoma | Adenoma, Prolactin-Secreting, Pituitary | Pituitary Adenoma, Prolactin-Secreting | Pituitary Adenoma, Prolactin Secreting | Pituitary Adenomas, Prolactin-Secreting | Prolactin-Secreting Pituitary Adenomas | Microprolactinoma | Microprolactinomas | Macroprolactinoma | Macroprolactinomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00165Aripiprazole0.000119%
BADD_D00304Bromocriptine0.001319%
BADD_D00329Cabergoline0.004804%
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D01281Levonorgestrel0.001182%
BADD_D01656Paliperidone0.006147%
BADD_D01951Risperidone0.000606%
BADD_D02464Fingolimod0.000241%
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