Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Intracranial hypotension
ADR ID BADD_A07954
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.01      Injuries NEC
12.01.10      Cerebral injuries NEC
12.01.10.008      Intracranial hypotension
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.05      Neurological signs and symptoms NEC
17.02.05.036      Intracranial hypotension
Description Reduction of CEREBROSPINAL FLUID pressure characterized clinically by ORTHOSTATIC HEADACHE and occasionally by an ABDUCENS NERVE PALSY; HEARING LOSS; NAUSEA; neck stiffness, and other symptoms. This condition may be spontaneous or secondary to CEREBROSPINAL FLUID LEAK; SPINAL PUNCTURE; NEUROSURGICAL PROCEDURES; DEHYDRATION; UREMIA; trauma (see also CRANIOCEREBRAL TRAUMA); and other processes. Chronic hypotension may be associated with subdural hematomas (see HEMATOMA, SUBDURAL) or hygromas. (From Semin Neurol 1996 Mar;16(1):5-10; Adams et al., Principles of Neurology, 6th ed, pp637-8) [MeSH]
MedDRA Code 10049977
MeSH ID D019585
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Intracranial hypotension | Low cerebrospinal fluid pressure syndrome | Intracranial Hypotension | Hypotension, Intracranial | Intracranial Hypotension, Secondary | Hypotension, Secondary Intracranial | Secondary Intracranial Hypotension | Intracranial Hypotension, Essential | Essential Intracranial Hypotension | Hypotension, Essential Intracranial | Intracranial Hypotension, Spontaneous | Hypotension, Spontaneous Intracranial | Spontaneous Intracranial Hypotension | Cerebrospinal Fluid Hypovolemia | Cerebrospinal Fluid Hypovolemias | Fluid Hypovolemia, Cerebrospinal | Fluid Hypovolemias, Cerebrospinal | Hypovolemia, Cerebrospinal Fluid | Hypovolemias, Cerebrospinal Fluid | CSF Hypovolemia | CSF Hypovolemias | Hypovolemia, CSF | Hypovolemias, CSF
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00209Baclofen0.000522%
BADD_D00560Cytarabine0.000112%
BADD_D00979Furosemide0.000028%
BADD_D02373Warfarin0.000070%
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