Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Acute chest syndrome
ADR ID BADD_A08070
ADR Hierarchy
01      Blood and lymphatic system disorders
01.04      Haemoglobinopathies
01.04.02      Sickle cell trait and disorders
01.04.02.004      Acute chest syndrome
22      Respiratory, thoracic and mediastinal disorders
22.06      Pulmonary vascular disorders
22.06.03      Vascular pulmonary disorders NEC
22.06.03.004      Acute chest syndrome
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.08      Pulmonary vascular disorders NEC
24.03.08.006      Acute chest syndrome
Description Respiratory syndrome characterized by the appearance of a new pulmonary infiltrate on chest x-ray, accompanied by symptoms of fever, cough, chest pain, tachypnea, or DYSPNEA, often seen in patients with SICKLE CELL ANEMIA. Multiple factors (e.g., infection, and pulmonary FAT EMBOLISM) may contribute to the development of the syndrome. [MeSH]
MedDRA Code 10051895
MeSH ID D056586
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acute chest syndrome | Acute Chest Syndrome | Acute Chest Syndromes | Syndrome, Acute Chest | Syndromes, Acute Chest
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00516Codeine0.000515%
BADD_D00594Deferasirox0.006815%
BADD_D01110Hydroxyurea0.000168%
BADD_D01228Ketamine0.000179%
BADD_D01498Morphine0.000390%
BADD_D01645Oxycodone0.000021%
BADD_D02411Voxelotor-
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