Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Primary hypogonadism
ADR ID BADD_A08122
ADR Hierarchy
05      Endocrine disorders
05.05      Endocrine disorders of gonadal function
05.05.04      Endocrine abnormalities of gonadal function NEC
05.05.04.009      Primary hypogonadism
21      Reproductive system and breast disorders
21.03      Sexual function and fertility disorders
21.03.02      Sexual function and fertility disorders NEC
21.03.02.025      Primary hypogonadism
Description Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism). [MeSH]
MedDRA Code 10052649
MeSH ID D007006
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Primary hypogonadism | Primary hypogenitalism | Hypergonadotropic hypogonadism | Primary gonadal failure | Hypogonadism | Hypogonadism, Isolated Hypogonadotropic | Hypogonadotropic Hypogonadism | Hypogonadism, Hypogonadotropic | Hypergonadotropic Hypogonadism | Hypogonadism, Hypergonadotropic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00854Etoposide--
BADD_D00898Finasteride0.000144%
BADD_D01376Melphalan0.000112%
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