Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pachymeningitis
ADR ID BADD_A08164
ADR Hierarchy
17      Nervous system disorders
17.06      Central nervous system infections and inflammations
17.06.03      Meningitis NEC
17.06.03.004      Pachymeningitis
Description Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6) [MeSH]
MedDRA Code 10053658
MeSH ID D008581
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hypertrophic pachymeningitis | Cerebral pachymeninx hypertrophy | Pachymeningitis | Meningitis | Meningitides | Pachymeningitides
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01110Hydroxyurea0.000112%
BADD_D02392Zoledronic acid0.010020%
BADD_D02464Fingolimod0.000241%
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