Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Fibrous histiocytoma
ADR ID BADD_A08168
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.26      Cutaneous neoplasms benign
16.26.01      Skin neoplasms benign
16.26.01.012      Fibrous histiocytoma
23      Skin and subcutaneous tissue disorders
23.10      Cutaneous neoplasms benign
23.10.01      Skin neoplasms benign
23.10.01.012      Fibrous histiocytoma
Description A benign tumor composed, wholly or in part, of cells with the morphologic characteristics of HISTIOCYTES and with various fibroblastic components. Fibrous histiocytomas can occur anywhere in the body. When they occur in the skin, they are called dermatofibromas or sclerosing hemangiomas. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 5th ed, p1747) | A slowly growing benign skin nodule consisting of poorly demarcated cellular fibrous tissue enclosing collapsed CAPILLARIES with scattered HEMOSIDERIN-pigmented and lipid MACROPHAGES. They are common, usually about 1 cm in diameter and occur in the DERMIS. (From Stedman, 25th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1356) [MeSH]
MedDRA Code 10053717
MeSH ID D018219; D051642
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Dermatofibroma | Dermatofibroma/histiocytoma | Histiocytoma | Fibrous histiocytoma | Fibroxanthoma | Histiocytoma, Benign Fibrous | Benign Fibrous Histiocytomas | Fibrous Histiocytoma, Benign | Fibrous Histiocytomas, Benign | Histiocytomas, Benign Fibrous | Benign Fibrous Histiocytoma | Histiocytoma, Fibrous | Fibrous Histiocytoma | Fibrous Histiocytomas | Histiocytomas, Fibrous | Dermatofibromas | Histiocytoma, Cutaneous | Cutaneous Histiocytoma | Cutaneous Histiocytomas | Histiocytomas, Cutaneous | Hemangioma, Sclerosing | Hemangiomas, Sclerosing | Sclerosing Hemangioma | Sclerosing Hemangiomas | Angioma, Sclerosing | Angiomas, Sclerosing | Sclerosing Angioma | Sclerosing Angiomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00898Finasteride0.000328%
BADD_D01136Imatinib0.000224%
BADD_D02344Vemurafenib0.000112%
BADD_D02464Fingolimod0.005642%
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