Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Right ventricular dysfunction
ADR ID BADD_A08365
ADR Hierarchy
02      Cardiac disorders
02.04      Myocardial disorders
02.04.02      Myocardial disorders NEC
02.04.02.033      Right ventricular dysfunction
Description A disorder characterized by impairment of right ventricular function associated with low ejection fraction and a decrease in motility of the right ventricular wall. [CTCAE] A condition in which the RIGHT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE or MYOCARDIAL INFARCTION, and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the right ventricular wall. [MeSH]
MedDRA Code 10058597
MeSH ID D018497
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Right ventricular dysfunction | Ventricular Dysfunction, Right | Right Ventricular Dysfunction | Dysfunction, Right Ventricular | Dysfunctions, Right Ventricular | Right Ventricular Dysfunctions | Ventricular Dysfunctions, Right
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00100Ambrisentan0.000265%
BADD_D00285Bosentan0.000530%
BADD_D00347Candesartan cilexetil0.000841%
BADD_D00474Cisplatin0.000112%
BADD_D00501Clonazepam0.000030%
BADD_D00563Dabigatran0.000367%
BADD_D00623Dexamethasone0.000291%
BADD_D00723Doxorubicin0.000448%
BADD_D00788Epoprostenol0.000082%
BADD_D00809Escitalopram0.000019%
BADD_D00879Fentanyl0.000211%
BADD_D00932Fluoxetine0.000039%
BADD_D01336Macitentan0.000181%
BADD_D01401Metformin0.000005%
BADD_D01864Propofol0.000179%
BADD_D01954Rivaroxaban0.000063%
BADD_D02105Tacrolimus0.000594%
BADD_D02236Tofacitinib0.000241%
BADD_D02268Treprostinil0.000082%
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