Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Diabetic foot
ADR ID BADD_A08468
ADR Hierarchy
05      Endocrine disorders
05.07      Diabetic complications
05.07.06      Diabetic complications dermal
05.07.06.001      Diabetic foot
14      Metabolism and nutrition disorders
14.07      Diabetic complications
14.07.06      Diabetic complications dermal
14.07.06.001      Diabetic foot
17      Nervous system disorders
17.09      Peripheral neuropathies
17.09.04      Chronic polyneuropathies
17.09.04.006      Diabetic foot
23      Skin and subcutaneous tissue disorders
23.07      Skin and subcutaneous tissue disorders NEC
23.07.03      Skin and subcutaneous tissue ulcerations
23.07.03.008      Diabetic foot
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.03      Peripheral vasoconstriction, necrosis and vascular insufficiency
24.04.03.015      Diabetic foot
Description Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION. [MeSH]
MedDRA Code 10060734
MeSH ID D017719
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Diabetic foot ulcer | Diabetic neuropathic ulcer | Diabetic ulcer NOS | Diabetic ulcer | Diabetic foot | Diabetic neuroischaemic ulcer | Diabetic neuroischemic ulcer | Neuroischemic diabetic foot | Neuroischaemic diabetic foot | Diabetic Foot | Foot, Diabetic | Diabetic Feet | Feet, Diabetic | Foot Ulcer, Diabetic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00036Acitretin--
BADD_D00151Apixaban0.000087%
BADD_D00285Bosentan0.000120%
BADD_D00344Canagliflozin0.005937%
BADD_D00349Capecitabine0.000280%
BADD_D00511Clozapine0.003057%
BADD_D00578Dapagliflozin0.001031%
BADD_D00765Empagliflozin0.001010%
BADD_D01119Ibrutinib0.000224%
BADD_D01336Macitentan0.000301%
BADD_D01401Metformin0.000019%
BADD_D01567Nilotinib0.000168%
BADD_D01676Paricalcitol0.012754%
BADD_D01835Pregabalin0.000332%
BADD_D02236Tofacitinib0.000723%
BADD_D02331Valsartan0.000053%
BADD_D02436Atorvastatin0.000023%
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