Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Ovarian epithelial cancer
ADR ID BADD_A08539
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.12      Reproductive neoplasms female malignant and unspecified
16.12.04      Ovarian neoplasms malignant (excl germ cell)
16.12.04.006      Ovarian epithelial cancer
21      Reproductive system and breast disorders
21.11      Ovarian and fallopian tube disorders
21.11.01      Ovarian and fallopian tube cysts and neoplasms
21.11.01.017      Ovarian epithelial cancer
Description A malignant neoplasm that originates in cells on the surface EPITHELIUM of the ovary and is the most common form of ovarian cancer. There are five histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Mutations in BRCA1, OPCML, PRKN, PIK3CA, AKT1, CTNNB1, RRAS2, and CDH1 genes are associated with this cancer. [MeSH]
MedDRA Code 10061328
MeSH ID D000077216
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Ovarian epithelial cancer NOS | Ovarian adenocarcinoma | Ovarian epithelial cancer | Carcinoma, Ovarian Epithelial | Carcinomas, Ovarian Epithelial | Epithelial Carcinoma, Ovarian | Epithelial Carcinomas, Ovarian | Ovarian Epithelial Carcinomas | Epithelial Ovarian Cancer | Ovarian Epithelial Cancer | Cancer, Ovarian Epithelial | Cancers, Ovarian Epithelial | Epithelial Cancer, Ovarian | Epithelial Cancers, Ovarian | Ovarian Epithelial Cancers | Ovarian Cancer, Epithelial | Cancer, Epithelial Ovarian | Cancers, Epithelial Ovarian | Epithelial Ovarian Cancers | Ovarian Cancers, Epithelial | Ovarian Epithelial Carcinoma | Epithelial Ovarian Carcinoma | Carcinoma, Epithelial Ovarian | Carcinomas, Epithelial Ovarian | Epithelial Ovarian Carcinomas | Ovarian Carcinoma, Epithelial | Ovarian Carcinomas, Epithelial
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01136Imatinib0.000224%
BADD_D01281Levonorgestrel0.000709%
BADD_D02192Thalidomide0.000241%
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