Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Eosinophilic oesophagitis
ADR ID BADD_A08737
ADR Hierarchy
01      Blood and lymphatic system disorders
01.02      White blood cell disorders
01.02.04      Eosinophilic disorders
01.02.04.016      Eosinophilic oesophagitis
07      Gastrointestinal disorders
07.08      Gastrointestinal inflammatory conditions
07.08.05      Oesophagitis (excl infective)
07.08.05.006      Eosinophilic oesophagitis
10      Immune system disorders
10.01      Allergic conditions
10.01.01      Allergies to foods, food additives, drugs and other chemicals
10.01.01.030      Eosinophilic oesophagitis
Description Chronic ESOPHAGITIS characterized by esophageal mucosal EOSINOPHILIA. It is diagnosed when an increase in EOSINOPHILS are present over the entire esophagus. The reflux symptoms fail to respond to PROTON PUMP INHIBITORS treatment, unlike in GASTROESOPHAGEAL REFLUX DISEASE. The symptoms are associated with IgE-mediated hypersensitivity to food or inhalant allergens. [MeSH]
MedDRA Code 10064212
MeSH ID D057765
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Eosinophilic oesophagitis | Eosinophilic esophagitis | Eosinophilic oesophagitis flare | Eosinophilic esophagitis flare | Eosinophilic Esophagitis | Eosinophilic Esophagitides | Esophagitides, Eosinophilic | Chronic Esophagitis, Eosinophilic | Chronic Esophagitides, Eosinophilic | Eosinophilic Chronic Esophagitides | Eosinophilic Chronic Esophagitis | Esophagitides, Eosinophilic Chronic | Esophagitis, Eosinophilic Chronic | Esophagitis, Eosinophilic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00356Carbamazepine0.000186%
BADD_D01120Ibuprofen0.000009%
BADD_D01213Isotretinoin0.000386%
BADD_D01272Levocetirizine0.000194%
BADD_D01285Levothyroxine0.000005%
BADD_D02105Tacrolimus0.001040%
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