Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Central nervous system necrosis
ADR ID BADD_A08810
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.10      Nervous system disorders NEC
17.02.10.020      Central nervous system necrosis
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.06      Cerebrovascular and spinal necrosis and vascular insufficiency
24.04.06.032      Central nervous system necrosis
Description A disorder characterized by a necrotic process occurring in the brain and/or spinal cord. [CTCAE]
MedDRA Code 10065784
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Central nervous system necrosis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00474Cisplatin0.000112%
BADD_D00648Diazepam0.000076%
BADD_D00932Fluoxetine0.000020%
BADD_D01401Metformin0.000005%
BADD_D01405Methadone0.000265%
BADD_D02150Temozolomide0.000783%
BADD_D02203Thiotepa0.000224%
BADD_D02480Alectinib0.000112%
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