Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Paradoxical embolism
ADR ID BADD_A08825
ADR Hierarchy
24      Vascular disorders
24.01      Embolism and thrombosis
24.01.01      Non-site specific embolism and thrombosis
24.01.01.031      Paradoxical embolism
Description Blockage of an artery due to passage of a clot (THROMBUS) from a systemic vein to a systemic artery without its passing through the lung which acts as a filter to remove blood clots from entering the arterial circulation. Paradoxical embolism occurs when there is a defect that allows a clot to cross directly from the right to the left side of the heart as in the cases of ATRIAL SEPTAL DEFECTS or open FORAMEN OVALE. Once in the arterial circulation, a clot can travel to the brain, block an artery, and cause a STROKE. [MeSH]
MedDRA Code 10066059
MeSH ID D019320
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Paradoxical embolism | Embolism, Paradoxical | Embolisms, Paradoxical | Paradoxical Embolisms | Paradoxical Embolism | Crossed Embolism | Crossed Embolisms | Embolism, Crossed | Embolisms, Crossed
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01470Minocycline0.000118%
BADD_D01599Olanzapine0.000842%
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