Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Velopharyngeal incompetence
ADR ID BADD_A08863
ADR Hierarchy
07      Gastrointestinal disorders
07.05      Oral soft tissue conditions
07.05.01      Oral soft tissue disorders NEC
07.05.01.020      Velopharyngeal incompetence
22      Respiratory, thoracic and mediastinal disorders
22.04      Upper respiratory tract disorders (excl infections)
22.04.05      Pharyngeal disorders (excl infections and neoplasms)
22.04.05.020      Velopharyngeal incompetence
Description Failure of the SOFT PALATE to reach the posterior pharyngeal wall to close the opening between the oral and nasal cavities. Incomplete velopharyngeal closure is primarily related to surgeries (ADENOIDECTOMY; CLEFT PALATE) or an incompetent PALATOPHARYNGEAL SPHINCTER. It is characterized by hypernasal speech. [MeSH]
MedDRA Code 10066790
MeSH ID D014681
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Velopharyngeal incompetence | Velopharyngeal Insufficiency | Insufficiency, Velopharyngeal | Palatopharyngeal Incompetence | Incompetence, Palatopharyngeal | Velopharyngeal Incompetence | Incompetence, Velopharyngeal | Inadequate Velopharyngeal Closure | Velopharyngeal Closures, Inadequate
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00932Fluoxetine0.000030%
BADD_D01645Oxycodone0.000041%
BADD_D01679Paroxetine0.000107%
BADD_D01834Prednisone0.000013%
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