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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
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KEGG ID
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ADR Ontology
ADR Term
Heart valve incompetence
ADR ID
BADD_A08925
ADR Hierarchy
02
Cardiac disorders
02.07
Cardiac valve disorders
02.07.02
Cardiac valve disorders NEC
02.07.02.003
Heart valve incompetence
Description
Not Available
MedDRA Code
10067660
MeSH ID
Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Cardiac valve leak | Heart valve insufficiency | Multi-valvular regurgitation | Heart valve incompetence | Heart valve regurgitation
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00066
Alendronic acid
0.000066%
BADD_D00100
Ambrisentan
0.000120%
BADD_D00285
Bosentan
0.000241%
BADD_D00501
Clonazepam
0.000030%
BADD_D00932
Fluoxetine
0.000030%
BADD_D01253
Lenalidomide
0.001664%
BADD_D01260
Leuprolide acetate
0.001434%
BADD_D01311
Lomitapide
0.000047%
BADD_D01336
Macitentan
0.000542%
BADD_D01445
Metoprolol
0.000015%
BADD_D01645
Oxycodone
0.000021%
BADD_D01679
Paroxetine
0.000043%
BADD_D01798
Pomalidomide
0.000530%
BADD_D01948
Riociguat
0.000120%
BADD_D01954
Rivaroxaban
0.000063%
BADD_D02010
Sertraline
0.000045%
BADD_D02047
Sodium oxybate
0.000402%
BADD_D02106
Tadalafil
0.000195%
BADD_D02236
Tofacitinib
0.000651%
BADD_D02268
Treprostinil
0.000082%
BADD_D02412
Octreotide
0.000186%
BADD_D02434
Cinacalcet
0.000782%
BADD_D02470
Nintedanib
0.000112%
BADD_D02568
Lutetium oxodotreotide lu-177
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