Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cerebral amyloid angiopathy
ADR ID BADD_A08956
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.05      Amyloidoses
10.02.05.003      Cerebral amyloid angiopathy
17      Nervous system disorders
17.08      Central nervous system vascular disorders
17.08.02      Central nervous system vascular disorders NEC
17.08.02.017      Cerebral amyloid angiopathy
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.05      Cerebrovascular and spinal vascular disorders NEC
24.03.05.010      Cerebral amyloid angiopathy
Description A heterogeneous group of sporadic or familial disorders characterized by AMYLOID deposits in the walls of small and medium sized blood vessels of CEREBRAL CORTEX and MENINGES. Clinical features include multiple, small lobar CEREBRAL HEMORRHAGE; cerebral ischemia (BRAIN ISCHEMIA); and CEREBRAL INFARCTION. Cerebral amyloid angiopathy is unrelated to generalized AMYLOIDOSIS. Amyloidogenic peptides in this condition are nearly always the same ones found in ALZHEIMER DISEASE. (from Kumar: Robbins and Cotran: Pathologic Basis of Disease, 7th ed., 2005) [MeSH]
MedDRA Code 10068044
MeSH ID D016657
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cerebral amyloid angiopathy | Congophilic angiopathy | Cerebral amyloid angiopathy related inflammation | Amyloid beta related angiitis | Cerebral Amyloid Angiopathy | Angiopathy, Cerebral Amyloid | Cerebral Amyloid Angiopathies | Congophilic Angiopathy | Angiopathy, Congophilic | Congophilic Angiopathies | Amyloid Angiopathy, Cerebral | Sporadic Cerebral Amyloid Angiopathy
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00151Apixaban0.000217%
BADD_D00551Cyclosporine0.000111%
BADD_D00563Dabigatran0.000245%
BADD_D01265Levetiracetam0.000119%
BADD_D01336Macitentan0.000265%
BADD_D01954Rivaroxaban0.000285%
BADD_D02373Warfarin0.000056%
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