Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Overlap syndrome
ADR ID BADD_A08992
ADR Hierarchy
10      Immune system disorders
10.04      Autoimmune disorders
10.04.04      Autoimmune disorders NEC
10.04.04.016      Overlap syndrome
15      Musculoskeletal and connective tissue disorders
15.06      Connective tissue disorders (excl congenital)
15.06.01      Connective tissue disorders NEC
15.06.01.016      Overlap syndrome
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.02      Connective tissue disorders
23.03.02.018      Overlap syndrome
Description Diseases that exhibit signs and symptoms suggestive of a connective tissue disease that do not fulfill clinical or diagnostic criteria for any one defined disease but overlap with criteria of multiple such diseases. Commonly overlapping diseases include systemic autoimmune connective tissue diseases such as RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; and SYSTEMIC SCLEROSIS. [MeSH]
MedDRA Code 10068786
MeSH ID D000074079
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Overlap syndrome | Undifferentiated Connective Tissue Diseases | Undifferentiated Connective Tissue Disease | Overlap Syndromes | Overlap Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00356Carbamazepine0.000744%
BADD_D00480Clarithromycin0.000223%
BADD_D00623Dexamethasone0.000145%
BADD_D01257Letrozole0.000395%
BADD_D01765Phenytoin0.000478%
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