Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Acute lung injury
ADR ID BADD_A09018
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.01      Lower respiratory tract disorders (excl obstruction and infection)
22.01.03      Pulmonary oedemas
22.01.03.010      Acute lung injury
Description A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). [MeSH]
MedDRA Code 10069351
MeSH ID D055371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acute lung injury | Acute Lung Injury | Acute Lung Injuries | Lung Injuries, Acute | Lung Injury, Acute
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam0.000019%
BADD_D00115Amiodarone0.000539%
BADD_D00194Azacitidine0.000112%
BADD_D00284Bortezomib0.000224%
BADD_D00312Bupropion0.000120%
BADD_D00480Clarithromycin0.000447%
BADD_D00501Clonazepam0.000074%
BADD_D00581Daptomycin0.000073%
BADD_D00648Diazepam0.000050%
BADD_D00686Diphenhydramine0.000336%
BADD_D00723Doxorubicin0.000168%
BADD_D00858Everolimus0.000306%
BADD_D00879Fentanyl0.001269%
BADD_D01295Linezolid0.003293%
BADD_D01397Mesalamine0.000274%
BADD_D01401Metformin0.000049%
BADD_D01405Methadone0.000398%
BADD_D01445Metoprolol0.000030%
BADD_D01498Morphine0.000390%
BADD_D01599Olanzapine0.000421%
BADD_D01629Osimertinib0.000112%
BADD_D01633Oxaliplatin0.000112%
BADD_D01645Oxycodone0.000062%
BADD_D01756Phentermine0.000109%
BADD_D01867Propranolol0.000080%
BADD_D02329Valproic acid0.000250%
BADD_D02348Verapamil0.000099%
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