Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Central nervous system vasculitis
ADR ID BADD_A09649
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.02      Vasculitides
10.02.02.030      Central nervous system vasculitis
17      Nervous system disorders
17.08      Central nervous system vascular disorders
17.08.02      Central nervous system vascular disorders NEC
17.08.02.029      Central nervous system vasculitis
24      Vascular disorders
24.12      Vascular infections and inflammations
24.12.04      Vasculitides NEC
24.12.04.005      Central nervous system vasculitis
Description Inflammation of blood vessels within the central nervous system. Primary vasculitis is usually caused by autoimmune or idiopathic factors, while secondary vasculitis is caused by existing disease process. Clinical manifestations are highly variable but include HEADACHE; SEIZURES; behavioral alterations; INTRACRANIAL HEMORRHAGES; TRANSIENT ISCHEMIC ATTACK; and BRAIN INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, pp856-61) [MeSH]
MedDRA Code 10081778
MeSH ID D020293
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cerebral phlebitis | Vasculitis cerebral | Central nervous system vasculitis | Primary central nervous system vasculitis | Spinal cord vasculitis | CNS vasculitis | Primary angiitis of the central nervous system | PACNS | Vasculitis, Central Nervous System | CNS Vasculitis | Vasculitis, CNS | Central Nervous System Angiitis | Angiitis, Central Nervous System | Central Nervous System Vasculitis | Secondary CNS Vasculitis | CNS Vasculitis, Secondary | Vasculitis, Secondary CNS | Vasculitis, CNS, Secondary | Postzoster Arteritis | Arteritis, Postzoster | Primary CNS Vasculitis | CNS Vasculitis, Primary | Vasculitis, Primary CNS | Primary Central Nervous System Vasculitis | Cerebral Angiitis | Angiitis, Cerebral | Cerebral Vasculitis | Vasculitis, Cerebral | Granulomatous Angiitis | Angiitis, Granulomatous | Granulomatous Arteritis | Arteritis, Granulomatous
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00130Amphetamine0.000120%
BADD_D00142Anastrozole0.000556%
BADD_D00637Dextroamphetamine sulfate--
BADD_D00912Fluconazole0.000045%
BADD_D01252Leflunomide0.000643%
BADD_D01431Methylphenidate0.000041%
BADD_D01470Minocycline--
BADD_D01834Prednisone0.000022%
BADD_D02098Sumatriptan--
BADD_D02099Sumatriptan succinate--
BADD_D02105Tacrolimus0.001040%
BADD_D02464Fingolimod0.000241%
BADD_D02473Sodium chloride--
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