Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Chronic cutaneous lupus erythematosus
ADR ID BADD_A09693
ADR Hierarchy
10      Immune system disorders
10.04      Autoimmune disorders
10.04.03      Lupus erythematosus and associated conditions
10.04.03.013      Chronic cutaneous lupus erythematosus
15      Musculoskeletal and connective tissue disorders
15.06      Connective tissue disorders (excl congenital)
15.06.02      Lupus erythematosus (incl subtypes)
15.06.02.013      Chronic cutaneous lupus erythematosus
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.02      Connective tissue disorders
23.03.02.022      Chronic cutaneous lupus erythematosus
Description A chronic form of cutaneous lupus erythematosus (LUPUS ERYTHEMATOSUS, CUTANEOUS) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur. [MeSH]
MedDRA Code 10057929
MeSH ID D008179; D015435
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Discoid lupus erythematosis | Discoid lupus erythematosus | Discoid lupus erythematosus of eyelid | DLE | LE-like discoid rash | Lupus erythematosis discoid | Lupus erythematosus discoid | Lupus erythematosus discoides | Discoid lupus erythematosus aggravated | Discoid lupus erythematosus aggr. | Chronic cutaneous lupus erythematosus | Chilblain lupus erythematosus | Lupus erythematosus profundus | Lupus erythematosus tumidus | Hypertrophic lupus erythematosus | Lupus erythematosus panniculitis | Discoid lupus erythematosus-lichen planus overlap syndrome | Lupus Erythematosus, Discoid | Discoid Lupus Erythematosus | Lupus Erythematosus, Chronic Cutaneous | Lupus Erythematosus, Cutaneous, Chronic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01142Imiquimod0.000658%
BADD_D01213Isotretinoin--
BADD_D01245Lansoprazole0.000149%
BADD_D02066Spironolactone0.000037%
BADD_D02165Teriflunomide0.000241%
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