Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Differentiation syndrome
ADR ID BADD_A09804
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.07      Oedema NEC
08.01.07.016      Differentiation syndrome
12      Injury, poisoning and procedural complications
12.03      Exposures, chemical injuries and poisoning
12.03.01      Poisoning and toxicity
12.03.01.063      Differentiation syndrome
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.32      Neoplasm related morbidities
16.32.03      Oncologic complications and emergencies
16.32.03.037      Differentiation syndrome
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.01      Breathing abnormalities
22.02.01.036      Differentiation syndrome
Description Not Available
MedDRA Code 10080638
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Retinoic acid syndrome | Acute promyelocytic leukaemia differentiation syndrome | APL differentiation syndrome | Acute promyelocytic leukemia differentiation syndrome | ATRA syndrome | IDH differentiation syndrome | Differentiation syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00036Acitretin0.003124%
BADD_D00168Arsenic--
BADD_D00169Arsenic trioxide0.001119%
BADD_D00194Azacitidine0.000783%
BADD_D00560Cytarabine0.000280%
BADD_D00593Decitabine0.000112%
BADD_D00623Dexamethasone0.000291%
BADD_D01480Mitoxantrone0.000112%
BADD_D01831Prednisolone0.000052%
BADD_D02270Tretinoin0.002721%
BADD_D02505Gilteritinib0.000783%
BADD_D02517Enasidenib0.002205%
BADD_D02524Ivosidenib0.000560%
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