Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Haemangioblastoma
ADR ID BADD_A09995
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.09      Nervous system neoplasms benign
16.09.01      Nervous system neoplasms benign NEC
16.09.01.006      Haemangioblastoma
17      Nervous system disorders
17.18      Nervous system neoplasms benign
17.18.01      Nervous system neoplasms benign NEC
17.18.01.006      Haemangioblastoma
Description A benign tumor of the nervous system that may occur sporadically or in association with VON HIPPEL-LINDAU DISEASE. It accounts for approximately 2% of intracranial tumors, arising most frequently in the cerebellar hemispheres and vermis. Histologically, the tumors are composed of multiple capillary and sinusoidal channels lined with endothelial cells and clusters of lipid-laden pseudoxanthoma cells. Usually solitary, these tumors can be multiple and may also occur in the brain stem, spinal cord, retina, and supratentorial compartment. Cerebellar hemangioblastomas usually present in the third decade with INTRACRANIAL HYPERTENSION, and ataxia. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2071-2) [MeSH]
MedDRA Code 10018813
MeSH ID D018325
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Haemangioblastoma | Hemangioblastoma | Hemangioblastomas | Multiple Hemangioblastomas | Hemangioblastoma, Multiple | Hemangioblastomas, Multiple | Multiple Hemangioblastoma
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00858Everolimus0.000153%
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