Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Histiocytic necrotising lymphadenitis
ADR ID BADD_A10041
ADR Hierarchy
01      Blood and lymphatic system disorders
01.13      Haematopoietic neoplasms (excl leukaemias and lymphomas)
01.13.02      Lymphoproliferative disorders NEC (excl leukaemias and lymphomas)
01.13.02.007      Histiocytic necrotising lymphadenitis
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.21      Haematopoietic neoplasms (excl leukaemias and lymphomas)
16.21.02      Lymphoproliferative disorders NEC (excl leukaemias and lymphomas)
16.21.02.007      Histiocytic necrotising lymphadenitis
Description Development of lesions in the lymph node characterized by infiltration of the cortex or paracortex by large collections of proliferating histiocytes and complete or, more often, incomplete necrosis of lymphoid tissue. [MeSH]
MedDRA Code 10069070
MeSH ID D020042
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Histiocytic necrotising lymphadenitis | Kikuchi disease | Histiocytic necrotizing lymphadenitis | Subacute necrotizing lymphadenitis | Subacute necrotising lymphadenitis | Histiocytic Necrotizing Lymphadenitis | Necrotizing Lymphadenitis, Histiocytic | Kikuchi Disease | Disease, Kikuchi | Kikuchi Necrotizing Lymphadenitis | Lymphadenitis, Kikuchi Necrotizing | Necrotizing Lymphadenitis, Kikuchi | Nosocomial Kikuchi's Disease | Kikuchi's Disease, Nosocomial | Nosocomial Kikuchi Disease | Nosocomial Kikuchis Disease | Kikuchi-Fujimoto Disease | Disease, Kikuchi-Fujimoto | Kikuchi Fujimoto Disease | Kikuchi-Fujimoto's Disease | Disease, Kikuchi-Fujimoto's | Kikuchi Fujimoto's Disease | Kikuchi-Fujimotos Disease | Lymphadenitis, Histiocytic Necrotizing | Histiocytic Necrotising Lymphadenitis | Histiocytic Necrotising Lymphadenitides | Lymphadenitides, Histiocytic Necrotising | Lymphadenitis, Histiocytic Necrotising | Necrotising Lymphadenitides, Histiocytic | Necrotising Lymphadenitis, Histiocytic | Kikuchi's Disease | Disease, Kikuchi's | Kikuchis Disease
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01243Lamotrigine0.000121%
BADD_D01831Prednisolone0.000035%
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