Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Mast cell activation syndrome
ADR ID BADD_A10361
ADR Hierarchy
01      Blood and lymphatic system disorders
01.05      Haematological disorders NEC
01.05.01      Haematological disorders
01.05.01.030      Mast cell activation syndrome
10      Immune system disorders
10.02      Immune disorders NEC
10.02.01      Immune and associated conditions NEC
10.02.01.090      Mast cell activation syndrome
Description A heterogenous group of disorders characterized by the abnormal increase of MAST CELLS in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA). [MeSH]
MedDRA Code 10075217
MeSH ID D008415
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Mast cell activation syndrome | Mastocytosis | Mastocytoses | Mast Cell Activation Syndrome | Mast Cell Activation Disease | Mast Cell Activation Syndromes | Mast Cell Disease | Mast Cell Diseases | Mast-Cell Disease | Mast-Cell Diseases
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00501Clonazepam0.000030%
BADD_D00869Famotidine0.000113%
BADD_D00932Fluoxetine0.000118%
BADD_D01086Hydrocortisone0.000046%
BADD_D01272Levocetirizine0.000130%
BADD_D01401Metformin0.000005%
BADD_D01496Montelukast0.000037%
BADD_D01834Prednisone0.000013%
BADD_D01867Propranolol0.000053%
BADD_D01913Ranitidine0.000025%
BADD_D02236Tofacitinib0.000362%
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