Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Obstructive sleep apnoea syndrome
ADR ID BADD_A10536
ADR Hierarchy
17      Nervous system disorders
17.15      Sleep disturbances (incl subtypes)
17.15.05      Sleep apnoeas
17.15.05.003      Obstructive sleep apnoea syndrome
19      Psychiatric disorders
19.02      Sleep disorders and disturbances
19.02.05      Dyssomnias
19.02.05.012      Obstructive sleep apnoea syndrome
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.01      Breathing abnormalities
22.02.01.038      Obstructive sleep apnoea syndrome
Description A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395) [MeSH]
MedDRA Code 10029983
MeSH ID D020181
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Obstructive sleep apnoea syndrome | Obstructive sleep apnea syndrome | Obstructive sleep apnea hypopnea syndrome | Obstructive sleep apnoea hypopnoea syndrome | Sleep Apnea, Obstructive | Apneas, Obstructive Sleep | Obstructive Sleep Apneas | Sleep Apneas, Obstructive | Obstructive Sleep Apnea Syndrome | Obstructive Sleep Apnea | OSAHS | Syndrome, Sleep Apnea, Obstructive | Sleep Apnea Syndrome, Obstructive | Apnea, Obstructive Sleep | Sleep Apnea Hypopnea Syndrome | Syndrome, Obstructive Sleep Apnea | Upper Airway Resistance Sleep Apnea Syndrome | Syndrome, Upper Airway Resistance, Sleep Apnea
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00471Ciprofloxacin--
BADD_D01253Lenalidomide--
BADD_D01285Levothyroxine--
BADD_D01498Morphine--
BADD_D02047Sodium oxybate0.000858%
BADD_D02107Tafamidis0.001346%
BADD_D02236Tofacitinib0.000241%
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