Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Osteochondrodysplasia
ADR ID BADD_A10577
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.11      Musculoskeletal and connective tissue disorders congenital
03.11.03      Non-site specific cartilage disorders congenital
03.11.03.002      Osteochondrodysplasia
15      Musculoskeletal and connective tissue disorders
15.11      Musculoskeletal and connective tissue disorders congenital
15.11.03      Non-site specific cartilage disorders congenital
15.11.03.002      Osteochondrodysplasia
Description An autosomal dominant disorder that is the most frequent form of short-limb dwarfism. Affected individuals exhibit short stature caused by rhizomelic shortening of the limbs, characteristic facies with frontal bossing and mid-face hypoplasia, exaggerated lumbar lordosis, limitation of elbow extension, GENU VARUM, and trident hand. (Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim, MIM#100800, April 20, 2001) [MeSH]
MedDRA Code 10087151
MeSH ID D000130; D010009
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Achondroplasia | Achondroplastic dwarf | Chondrodystrophy | Congenital dwarfism | Achondrogenesis | Osteochondrodysplasia | Achondroplasias | Achondroplasia, Severe, With Developmental Delay And Acanthosis Nigricans | Skeleton-Skin-Brain Syndrome | Skeleton Skin Brain Syndrome | Skeleton-Skin-Brain Syndromes | Syndrome, Skeleton-Skin-Brain | Syndromes, Skeleton-Skin-Brain | Severe Achondroplasia with Developmental Delay and Acanthosis Nigricans | SADDAN | SADDANs | SADDAN Dysplasia | Dysplasia, SADDAN | Dysplasias, SADDAN | SADDAN Dysplasias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00932Fluoxetine--
BADD_D01149Indapamide--
BADD_D01835Pregabalin--
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