Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Renal tubular dysfunction
ADR ID BADD_A10839
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.03      Nephropathies and tubular disorders NEC
20.05.03.028      Renal tubular dysfunction
Description A hereditary or acquired form of generalized dysfunction of the PROXIMAL KIDNEY TUBULE without primary involvement of the KIDNEY GLOMERULUS. It is usually characterized by the tubular wasting of nutrients and salts (GLUCOSE; AMINO ACIDS; PHOSPHATES; and BICARBONATES) resulting in HYPOKALEMIA; ACIDOSIS; HYPERCALCIURIA; and PROTEINURIA. [MeSH]
MedDRA Code 10050335
MeSH ID D005198
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Distal renal tubular dysfunction | Proximal renal tubular dysfunction | Renal tubular dysfunction | Fanconi Syndrome | Syndrome, Fanconi | Proximal Renal Tubular Dysfunction | Toni-Debre-Fanconi Syndrome | Primary Toni-Debre-Fanconi Syndrome | Neonatal De Toni-Debre-Fanconi Syndrome | De Toni-Debre-Fanconi Syndrome | Idiopathic De Toni-Debre-Fanconi Syndrome | Fanconi Bickel Syndrome | Bickel Syndrome, Fanconi | Syndrome, Fanconi Bickel | Fanconi-Bickel Syndrome | Fanconi-Bickel Syndromes | Syndrome, Fanconi-Bickel | Syndromes, Fanconi-Bickel | Glycogen Storage Disease XI | Pseudo-Phlorizin Diabetes | Diabete, Pseudo-Phlorizin | Diabetes, Pseudo-Phlorizin | Pseudo Phlorizin Diabetes | Pseudo-Phlorizin Diabete | Hepatic Glycogenosis with Amino Aciduria and Glucosuria | Hepatic Glycogenosis with Fanconi Nephropathy | Hepatorenal Glycogenosis with Renal Fanconi Syndrome | Lignac-Fanconi Syndrome | Lignac Fanconi Syndrome | Syndrome, Lignac-Fanconi | Fanconi Syndrome with Intestinal Malabsorption and Galactose Intolerance | Glycogenosis, Fanconi Type | Fanconi Type Glycogenosis | Fanconi Syndrome without Cystinosis | Renal Fanconi Syndrome | Fanconi Syndrome, Renal | Syndrome, Renal Fanconi | Luder-Sheldon Syndrome | Luder Sheldon Syndrome | Syndrome, Luder-Sheldon | Adult Fanconi Syndrome | Fanconi Syndrome, Adult | Syndrome, Adult Fanconi | Fanconi Renotubular Syndrome | Renotubular Syndrome, Fanconi | Syndrome, Fanconi Renotubular
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00044Adefovir dipivoxil0.001976%
BADD_D00474Cisplatin0.000224%
BADD_D00594Deferasirox0.001239%
BADD_D01136Imatinib0.000224%
BADD_D01401Metformin0.000005%
BADD_D02053Sofosbuvir0.001129%
BADD_D02105Tacrolimus0.000297%
BADD_D02147Telmisartan0.000521%
BADD_D02154Tenofovir0.031989%
BADD_D02247Topiramate0.000101%
BADD_D02392Zoledronic acid0.011452%
The 1th Page    1    Total 1 Pages