Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Silent thyroiditis
ADR ID BADD_A10917
ADR Hierarchy
05      Endocrine disorders
05.02      Thyroid gland disorders
05.02.04      Acute and chronic thyroiditis
05.02.04.006      Silent thyroiditis
10      Immune system disorders
10.04      Autoimmune disorders
10.04.08      Endocrine autoimmune disorders
10.04.08.017      Silent thyroiditis
18      Pregnancy, puerperium and perinatal conditions
18.02      Maternal complications of pregnancy
18.02.02      Maternal complications of pregnancy NEC
18.02.02.024      Silent thyroiditis
Description Transient autoimmune thyroiditis occurring in the POSTPARTUM PERIOD. It is characterized by the presence of high titers of AUTOANTIBODIES against THYROID PEROXIDASE and THYROGLOBULIN. Clinical signs include the triphasic thyroid hormone pattern: beginning with THYROTOXICOSIS, followed with HYPOTHYROIDISM, then return to euthyroid state by 1 year postpartum. [MeSH]
MedDRA Code 10079012
MeSH ID D050032
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Silent thyroiditis | Subacute lymphocytic thyroiditis | Postpartum thyroiditis | Postpartum Thyroiditis | Postpartum Thyroiditides | Thyroiditides, Postpartum | Thyroiditis, Postpartum | Post-partum Thyroiditis | Post partum Thyroiditis | Post-partum Thyroiditides | Thyroiditides, Post-partum | Thyroiditis, Post-partum
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01254Lenvatinib0.000112%
BADD_D01285Levothyroxine0.000005%
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