Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Abiraterone
Drug ID BADD_D00014
Description Abiraterone is a derivative of steroidal progesterone and is an innovative drug that offers clinical benefit to patients with hormone refractory prostate cancer. Abiraterone is administered as an acetate salt prodrug because it has a higher bioavailability and less susceptible to hydrolysis than abiraterone itself. FDA approved on April 28, 2011.
Indications and Usage Used in combination with prednisone for the treatment of metastatic, castration-resistant prostate cancer.
Marketing Status approved
ATC Code L02BX03
DrugBank ID DB05812
KEGG ID Not Available
MeSH ID C089740
PubChem ID 132971
TTD Drug ID D02STN
NDC Product Code 42291-024; 42291-073; 69238-1754; 60219-1754; 60687-455; 17337-0082; 54893-0070; 30007-838; 69238-1165; 60219-1165
UNII G819A456D0
Synonyms abiraterone | 17-(3-pyridyl)androsta-5,16-dien-3beta-ol | CB-7598 | CB 7598 | CB7598
Chemical Information
Molecular Formula C24H31NO
CAS Registry Number 154229-19-3
SMILES CC12CCC(CC1=CCC3C2CCC4(C3CC=C4C5=CN=CC=C5)C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain upper07.01.05.003--
Abnormal faeces07.01.03.0010.000901%Not Available
Acute leukaemia16.01.02.001; 01.10.02.0010.000334%Not Available
Acute myocardial infarction24.04.04.001; 02.02.02.001--Not Available
Acute pulmonary oedema22.01.03.005; 02.05.02.0040.001668%Not Available
Addison's disease14.11.01.025; 10.04.08.008; 05.01.02.0060.000667%Not Available
Adrenal insufficiency14.11.01.004; 05.01.02.0010.002569%
Ageusia17.02.07.001; 07.14.03.0030.005439%Not Available
Alanine aminotransferase increased13.03.04.005--
Amnesia19.20.01.001; 17.03.02.0010.010477%
Anaemia01.03.02.0010.015416%
Angina unstable24.04.04.004; 02.02.02.0040.000334%Not Available
Anosmia22.04.03.006; 17.04.04.0010.000734%
Aortic dissection24.02.03.0020.000834%Not Available
Aortic stenosis24.04.01.0010.000334%Not Available
Aplastic anaemia01.03.03.0020.000334%Not Available
Arrhythmia02.03.02.0010.005606%Not Available
Arrhythmia supraventricular02.03.03.0010.000501%Not Available
Arthropathy15.01.01.003--Not Available
Aspartate aminotransferase increased13.03.04.011--
Aspiration22.02.07.007--
Asthenia08.01.01.0010.046681%Not Available
Atrial fibrillation02.03.03.0020.009243%
Atrial flutter02.03.03.0030.000501%
Bile duct stone09.02.02.0030.000334%Not Available
Blindness unilateral06.02.10.007; 17.17.01.0160.000901%Not Available
Blood potassium decreased13.11.01.010--Not Available
Blood triglycerides increased13.12.03.001--Not Available
Body temperature increased13.15.01.001--Not Available
The 1th Page    1 2 3 4 5    Next   Last    Total 12 Pages