| Pharmaceutical Information |
| Drug Name |
Acyclovir sodium |
| Drug ID |
BADD_D00040 |
| Description |
Acyclovir is a nucleotide analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis[L7303,L7315,L7318,L7321,L7324,L7327]. Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old.[L7321]
Acyclovir was granted FDA approval on 29 March 1982.[L7318] |
| Indications and Usage |
An acyclovir topical cream is indicated to treat recurrent herpes labialis in immunocompetent patients 12 years and older.[L7303] Acyclovir oral tablets, capsules, and suspensions are indicated to treat herpes zoster, genital herpes, and chickenpox.[L7315] An acyclovir topical ointment is indicated to treat initial genital herpes and limited non-life-threatening mucocutaneous herpes simplex in immunocompromised patients.[L7318] An acyclovir cream with hydrocortisone is indicated to treat recurrent herpes labialis, and shortening lesion healing time in patients 6 years and older.[L7321] An acyclovir buccal tablet is indicated for the treatment of recurrent herpes labialis.[L7324] An acyclovir ophthalmic ointment is indicated to treat acute herpetic keratitis.[L7327] |
| Marketing Status |
approved |
| ATC Code |
S01AD03; J05AB01; D06BB03 |
| DrugBank ID |
DB00787
|
| KEGG ID |
D02764
|
| MeSH ID |
D000212
|
| PubChem ID |
23665721
|
| TTD Drug ID |
D0B5MP
|
| NDC Product Code |
63323-325; 14335-150; 55150-154; 55150-155; 46014-1019 |
| UNII |
927L42J563
|
| Synonyms |
Acyclovir | 9-((2-Hydroxyethoxy)methyl)guanine | Aciclovir | Acycloguanosine | Herpoviric | Aciclobeta | Aciclostad | Isavir | Laciken | Mapox | Maynar | Milavir | Opthavir | Supraviran | Viclovir | Vipral | Virax-Puren | Virax Puren | ViraxPuren | Virherpes | Virmen | Virolex | Virupos | Virzin | Wellcome-248U | Wellcome 248U | Wellcome248U | Zoliparin | Zovirax | Zyclir | Aciclovir Alonga | Alonga, Aciclovir | Acifur | Acipen Solutab | Solutab, Acipen | Acivir | Activir | Acyclo-V | Acyclo V | Acyclovir Sodium | Sodium, Acyclovir | Antiherpes Creme | aciclovir von ct | Avirax | Cicloferon | Clonorax | Cusiviral | Genvir | Herpetad | Herpofug | Herpotern | Aci-Sanorania | Aci Sanorania | Aciclovir-Sanorania | Aciclovir Sanorania | Acic |
|
| Chemical Information |
| Molecular Formula |
C8H10N5NaO3 |
| CAS Registry Number |
69657-51-8 |
| SMILES |
C1=NC2=C(N1COCCO)N=C(N=C2[O-])N.[Na+] |
| Chemical Structure |
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| ADRs Induced by Drug |
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