Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alfentanil
Drug ID BADD_D00067
Description A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Indications and Usage For the management of postoperative pain and the maintenance of general anesthesia.
Marketing Status Prescription
ATC Code N01AH02
DrugBank ID DB00802
KEGG ID D07122
MeSH ID D015760
PubChem ID 51263
TTD Drug ID D0G5QB
NDC Product Code Not Available
Synonyms Alfentanil | Alfentanyl | Alfentanil Hydrochloride | R-39209 | R 39209 | R39209 | Alfenta | Limifen | Rapifen | Fanaxal
Chemical Information
Molecular Formula C21H32N6O3
CAS Registry Number 71195-58-9
SMILES CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCN3C(=O)N(N=N3)CC)COC
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Headache17.14.01.001--
Hiccups22.02.04.002; 07.01.06.009--
Hypercapnia22.02.02.002; 14.01.04.001--Not Available
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Immune system disorder10.02.01.001--Not Available
Injection site pain12.07.03.011; 08.02.03.010--Not Available
Laryngospasm22.04.02.002--
Loss of consciousness17.02.04.004--Not Available
Movement disorder17.01.02.010--Not Available
Muscle rigidity17.05.02.005; 15.05.04.001--Not Available
Myoclonus17.02.05.008--Not Available
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Pain08.01.08.004--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Respiratory arrest22.02.01.009--Not Available
Respiratory depression22.02.01.010; 17.02.05.047--Not Available
Respiratory rate decreased13.15.01.003--Not Available
Seizure17.12.03.001--
Skin disorder23.03.03.007--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Tachycardia02.03.02.007--Not Available
Unresponsive to stimuli17.02.05.031--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vascular pain24.03.02.026--Not Available
Vision blurred17.17.01.010; 06.02.06.007--
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