| Pharmaceutical Information |
| Drug Name |
Alvimopan |
| Drug ID |
BADD_D00096 |
| Description |
Alvimopan is a peripherally acting μ opioid antagonist. It is used to avoid postoperative ileus following small or large bowel resection and accelerates the gastrointestinal recovery period. |
| Indications and Usage |
Used to accelerate the time to upper and lower gastrointestinal recovery following partial large or small bowel resection surgery with primary anastomosis. Also investigated for use in the treatment of pain (acute or chronic). |
| Marketing Status |
approved; investigational |
| ATC Code |
A06AH02 |
| DrugBank ID |
DB06274
|
| KEGG ID |
D02878
|
| MeSH ID |
C419502
|
| PubChem ID |
5488548
|
| TTD Drug ID |
D0D7KC
|
| NDC Product Code |
67919-020; 0591-2312; 55679-111; 0254-3012 |
| UNII |
677C126AET
|
| Synonyms |
alvimopan | trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine | alvimopan anhydrous | anhydrous alvimopan | LY 246736 | LY246736 | LY-246736 | ADL 8-2698 | ADL8-2698 | Entereg |
|
| Chemical Information |
| Molecular Formula |
C25H32N2O4 |
| CAS Registry Number |
156053-89-3 |
| SMILES |
CC1CN(CCC1(C)C2=CC(=CC=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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