Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Aminocaproic acid
Drug ID BADD_D00106
Description An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Indications and Usage For use in the treatment of excessive postoperative bleeding.
Marketing Status approved; investigational
ATC Code B02AA01
DrugBank ID DB00513
KEGG ID D00160
MeSH ID D015119
PubChem ID 564
TTD Drug ID D0FD0H
NDC Product Code 59285-019; 69766-054; 0517-9120; 0517-9191; 72205-049; 47621-310; 60687-529; 69238-1637; 69539-161; 69680-116; 80005-128; 46438-0641; 54288-151; 60687-739; 0404-9812; 69680-115; 70377-104; 76055-0030; 17478-447; 49411-050; 80005-129; 65571-0025; 70966-0010; 31722-035; 42799-054; 49411-052; 0409-4346; 62559-225; 69238-1596; 73216-110; 71052-265; 17478-768; 59651-573; 60687-724; 66689-330; 70377-102; 70377-103; 80005-130; 17478-769; 73216-111; 0904-7165; 72572-015; 49411-051; 51672-4226; 52817-815
UNII U6F3787206
Synonyms Aminocaproic Acid | 6-Aminohexanoic Acid | 6 Aminohexanoic Acid | epsilon-Aminocaproic Acid | epsilon Aminocaproic Acid | 6-Aminocaproic Acid | 6 Aminocaproic Acid | Capralense | Capramol | Caproamin | Caprocid | Hexalense | CY-116 | CY 116 | CY116 | Epsamon | Epsikapron | Hemocaprol | Amicar | Caprolest
Chemical Information
Molecular Formula C6H13NO2
CAS Registry Number 60-32-2
SMILES C(CCC(=O)O)CCN
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Respiratory failure22.02.06.002; 14.01.04.0030.000229%
Rhabdomyolysis15.05.05.002--
Seizure17.12.03.0010.001120%
Shock24.06.02.002--Not Available
Swelling08.01.03.0150.000229%Not Available
Syncope24.06.02.012; 17.02.04.008; 02.11.04.015--
Thrombocytopenia01.08.01.002--Not Available
Thrombosis24.01.01.006--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Visual acuity reduced06.02.10.012; 17.17.01.011--
Vomiting07.01.07.003--
Factor VIII inhibition01.01.02.0120.000457%Not Available
Poor venous access24.03.02.0170.000229%Not Available
Peripheral swelling08.01.03.053; 02.05.04.0150.000229%Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Haemorrhage24.07.01.0020.000686%Not Available
Ill-defined disorder08.01.03.049--Not Available
Heparin-induced thrombocytopenia10.02.01.007; 01.08.01.004; 24.01.01.0200.000457%Not Available
Acute kidney injury20.01.03.0160.000457%
Spontaneous haemorrhage24.07.01.081; 01.01.03.0070.000229%Not Available
Drug ineffective for unapproved indication12.09.02.002; 08.06.01.0380.000229%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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