| Pharmaceutical Information |
| Drug Name |
Aminophylline |
| Drug ID |
BADD_D00112 |
| Description |
Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD. The majority of aminophylline medications are discontinued and the remaining medications on the market are in short supply. |
| Indications and Usage |
For the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. |
| Marketing Status |
approved |
| ATC Code |
R03DA05 |
| DrugBank ID |
DB01223
|
| KEGG ID |
D00227
|
| MeSH ID |
D000628
|
| PubChem ID |
9433
|
| TTD Drug ID |
D03TYI
|
| NDC Product Code |
51662-1204; 0404-9813; 71872-7060; 0409-5922; 0409-5921; 52584-922; 0404-9814; 51662-1341; 52584-921; 73212-047; 71872-7121; 58624-0544 |
| UNII |
27Y3KJK423
|
| Synonyms |
Aminophylline | Theophylline Ethylenediamine | Ethylenediamine, Theophylline | Theophyllamine | Phyllotemp | Mundiphyllin | Theophyllamin Jenapharm | Theophyllin EDA-ratiopharm | Theophyllin EDA ratiopharm | Theophyllin EDAratiopharm | Truphylline | Afonilum | Carine | Eufilina | Euphyllin | Aminodur | Aminophyllin | Aminophylline DF | Cardophyllin | Clonofilin | Corophyllin | Diaphyllin | Drafilyn | Duraphyllin | Eufilina Venosa | Euphyllin Retard | Euphylline | Godafilin | Mini-Lix | Mundiphyllin Retard | Novophyllin | Phyllocontin | Somophyllin | Tari-Dog |
|
| Chemical Information |
| Molecular Formula |
C16H24N10O4 |
| CAS Registry Number |
317-34-0 |
| SMILES |
CN1C2=C(C(=O)N(C1=O)C)NC=N2.CN1C2=C(C(=O)N(C1=O)C)NC=N2.C(CN)N |
| Chemical Structure |
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| ADRs Induced by Drug |
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