Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ascorbic acid
Drug ID BADD_D00171
Description A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Indications and Usage Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.
Marketing Status approved; nutraceutical
ATC Code G01AD03; S01XA15
DrugBank ID DB00126
KEGG ID D00018
MeSH ID D001205
PubChem ID 54670067
TTD Drug ID D07AHW
NDC Product Code 63083-1505; 67157-101; 72783-1001; 63238-3000; 51552-0164; 49452-0742; 10695-126; 62512-0020; 51927-5098
UNII PQ6CK8PD0R
Synonyms Ascorbic Acid | Acid, Ascorbic | L-Ascorbic Acid | Acid, L-Ascorbic | L Ascorbic Acid | Vitamin C | Hybrin | Magnorbin | Sodium Ascorbate | Ascorbate, Sodium | Ascorbic Acid, Monosodium Salt | Ferrous Ascorbate | Ascorbate, Ferrous | Magnesium Ascorbate | Ascorbate, Magnesium | Magnesium di-L-Ascorbate | Magnesium di L Ascorbate | di-L-Ascorbate, Magnesium | Magnesium Ascorbicum
Chemical Information
Molecular Formula C6H8O6
CAS Registry Number 50-81-7
SMILES C(C(C1C(=C(C(=O)O1)O)O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Feeling cold08.01.09.0080.000496%Not Available
Feeling hot08.01.09.0090.001338%Not Available
Fistula15.03.02.001--Not Available
Flatulence07.01.04.0020.000743%
Flushing24.03.01.002; 23.06.05.003; 08.01.03.0250.000743%
Gait disturbance15.03.05.013; 17.02.05.016; 08.01.02.0020.001338%
Gallbladder disorder09.03.02.0010.000496%Not Available
Generalised oedema14.05.06.007; 08.01.07.004--
Gingival pain07.09.13.010--
Haematochezia24.07.02.012; 07.12.02.003--Not Available
Headache17.14.01.0010.006196%
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hyperhidrosis08.01.03.028; 23.02.03.0040.002429%
Hypersensitivity10.01.03.0030.000991%
Hypertension24.08.02.0010.001090%
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hypokalaemia14.05.03.0020.000743%
Hypotension24.06.03.0020.000991%
Influenza like illness08.01.03.0100.001090%
Injection site bruising24.07.06.017; 23.03.11.015; 12.07.03.042; 08.02.03.042--Not Available
Injection site erythema12.07.03.001; 08.02.03.001; 23.03.06.0150.001685%Not Available
Injection site haemorrhage12.07.03.005; 08.02.03.005; 24.07.01.010--Not Available
Injection site induration12.07.03.007; 08.02.03.007--Not Available
Injection site pain12.07.03.011; 08.02.03.010--Not Available
Injection site rash23.03.13.010; 12.07.03.032; 08.02.03.0320.001685%Not Available
Injection site reaction12.07.03.015; 08.02.03.0140.001685%
Insomnia19.02.01.002; 17.15.03.0020.001090%
Irritability19.04.02.013; 08.01.03.0110.001933%
Lip swelling23.04.01.007; 10.01.05.005; 07.05.04.0050.000496%Not Available
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